Cholesterol Pathways Affected by Small Molecules That Decrease Sterol Levels in Niemann-Pick Type C Mutant Cells

Eitemau Tebyg

• Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells
  gan: Pipalia, Nina H., et al.
  Cyhoeddwyd: (2017)
• CHEMICAL SCREEN TO REDUCE STEROL ACCUMULATION IN NIEMANN-PICK C DISEASE CELLS IDENTIFIES NOVEL LYSOSOMAL ACID LIPASE INHIBITORS
  gan: Rosenbaum, Anton I., et al.
  Cyhoeddwyd: (2009)
• Therapeutic potential of histone deacetylase inhibitor for treatment of Niemann-Pick type C1 disease
  gan: Pipalia, Nina H, et al.
  Cyhoeddwyd: (2014)
• Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
  gan: Pipalia, Nina H., et al.
  Cyhoeddwyd: (2011)
• Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells
  gan: Rosenbaum, Anton I., et al.
  Cyhoeddwyd: (2010)