Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

Chloroquine resistance in Plasmodium falciparum is primarily conferred by mutations in pfcrt. Parasites resistant to chloroquine can display hypersensitivity to other antimalarials; however, the patterns of cross-resistance are complex, and the genetic basis has remained elusive. We show that stepwi...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Johnson, David J., Fidock, David A., Mungthin, Mathirut, Lakshmanan, Viswanathan, Sidhu, Amar Bir Singh, Bray, Patrick G., Ward, Stephen A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2004
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943419/
https://ncbi.nlm.nih.gov/pubmed/15383277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2004.09.012
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller