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Regulation of Opioid Tolerance by let-7 Family MicroRNA Targeting the μ Opioid Receptor
MicroRNA has emerged as a critical regulator of neuronal functions. This study aimed to test whether let-7 microRNAs can regulate the μ opioid receptor (MOR) and opioid tolerance. Employing bioinformatics, we identified a let-7 binding site in the 3′-untranslated region (UTR) of MOR mRNA, which was...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943348/ https://ncbi.nlm.nih.gov/pubmed/20668208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2419-10.2010 |
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