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A Bicarbonate Cofactor Modulates 1,4-Dihydroxy-2-naphthoyl-Coenzyme A Synthase in Menaquinone Biosynthesis of Escherichia coli

1,4-Dihydroxy-2-naphthoyl coenzyme A (DHNA-CoA) synthase is a typical crotonase-fold protein catalyzing an intramolecular Claisen condensation in the menaquinone biosynthetic pathway. We have characterized this enzyme from Escherichia coli and found that it is activated by bicarbonate in a concentra...

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Detalhes bibliográficos
Main Authors: Jiang, Ming, Chen, Minjiao, Guo, Zu-Feng, Guo, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943303/
https://ncbi.nlm.nih.gov/pubmed/20643650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147702
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