B55α PP2A Holoenzymes Modulate the Phosphorylation Status of the Retinoblastoma-related Protein p107 and Its Activation

Pocket proteins negatively regulate transcription of E2F-dependent genes and progression through the G(0)/G(1) transition and the cell cycle restriction point in G(1). Pocket protein repressor activities are inactivated via phosphorylation at multiple Pro-directed Ser/Thr sites by the coordinated ac...

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Main Authors: Jayadeva, Girish, Kurimchak, Alison, Garriga, Judit, Sotillo, Elena, Davis, Anthony J., Haines, Dale S., Mumby, Marc, Graña, Xavier
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943288/
https://ncbi.nlm.nih.gov/pubmed/20663872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162354
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