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Oncogenic NRAS Cooperates with p53 Loss to Generate Melanoma in Zebrafish
NRAS mutations are a common oncogenic event in skin cancer, occurring frequently in congenital nevi and malignant melanoma. To study the role of NRAS in zebrafish, a transgenic approach was applied to generate fish that express human oncogenic NRAS(Q61K) under the control of the melanocyte-restricte...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943216/ https://ncbi.nlm.nih.gov/pubmed/19954345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2009.0606 |
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