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Oncogenic NRAS Cooperates with p53 Loss to Generate Melanoma in Zebrafish

NRAS mutations are a common oncogenic event in skin cancer, occurring frequently in congenital nevi and malignant melanoma. To study the role of NRAS in zebrafish, a transgenic approach was applied to generate fish that express human oncogenic NRAS(Q61K) under the control of the melanocyte-restricte...

詳細記述

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書誌詳細
主要な著者: Dovey, Michael, White, Richard Mark, Zon, Leonard I.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943216/
https://ncbi.nlm.nih.gov/pubmed/19954345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2009.0606
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