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Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptors

The ligands of certain G-protein coupled receptors (GPCRs) are membrane soluble and reach their target from the lipid bilayer. Lipid composition and dynamics will therefore modulate the activity of these receptors, but specific roles of lipid components, including the ubiquitous cholesterol (Chol),...

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Bibliografski detalji
Glavni autori: Khelashvili, George, Mondal, Sayan, Andersen, Olaf S., Weinstein, Harel
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943214/
https://ncbi.nlm.nih.gov/pubmed/20804205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp106373r
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