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Membrane Driven Spatial Organization of GPCRs
Spatial organization of G-protein coupled receptors (GPCRs) into dimers and higher order oligomers has been demonstrated in vitro and in vivo. The pharmacological readout was shown to depend on the specific interfaces, but why particular regions of the GPCR structure are involved, and how ligand-det...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793225/ https://ncbi.nlm.nih.gov/pubmed/24105260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02909 |
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