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Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptors
The ligands of certain G-protein coupled receptors (GPCRs) are membrane soluble and reach their target from the lipid bilayer. Lipid composition and dynamics will therefore modulate the activity of these receptors, but specific roles of lipid components, including the ubiquitous cholesterol (Chol),...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943214/ https://ncbi.nlm.nih.gov/pubmed/20804205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp106373r |
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