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Anti-cancer gallotannin penta-O-galloyl-beta-D-glucose is a nanomolar inhibitor of select mammalian DNA polymerases

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose (PGG) has been shown by us and others to inhibit the in vivo growth of human prostate cancer (PCa) xenografts in athymic nude mice and mouse lung cancer allograft in syngenic mice without evident adverse effect on their body weight. We observed a rapid inhibi...

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Détails bibliographiques
Auteurs principaux: Mizushina, Yoshiyuki, Zhang, Jinhui, Pugliese, Angelo, Kim, Sung-Hoon, Lü, Junxuan
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943143/
https://ncbi.nlm.nih.gov/pubmed/20599777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.031
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