Preparation of Penta-O-galloyl-β-D-glucose from tannic acid and plasma pharmacokinetic Analyses by Liquid-Liquid Extraction and Reverse-Phase HPLC

Eitemau Tebyg

• Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose
  gan: Zhang, Jinhui, et al.
  Cyhoeddwyd: (2009)
• Anti-cancer gallotannin penta-O-galloyl-beta-D-glucose is a nanomolar inhibitor of select mammalian DNA polymerases
  gan: Mizushina, Yoshiyuki, et al.
  Cyhoeddwyd: (2010)
• Penta-O-galloyl-β-D-glucose induces G(1 )arrest and DNA replicative S-phase arrest independently of P21 cyclin-dependent kinase inhibitor 1A, P27 cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple-negative xenograft growth
  gan: Chai, Yubo, et al.
  Cyhoeddwyd: (2010)
• Penta-O-galloyl-beta-D-glucose induces S- and G(1)-cell cycle arrests in prostate cancer cells targeting DNA replication and cyclin D1
  gan: Hu, Hongbo, et al.
  Cyhoeddwyd: (2009)
• Penta-galloyl-glucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells
  gan: Hu, Hongbo, et al.
  Cyhoeddwyd: (2009)