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Preparation of Penta-O-galloyl-β-D-glucose from tannic acid and plasma pharmacokinetic Analyses by Liquid-Liquid Extraction and Reverse-Phase HPLC

The gallotannin penta-O-galloyl-beta-D-glucose (PGG) has many biological activities including in vivo anti-cancer efficacy. We present in this paper a scaled-up protocol for its preparation in high purity from tannic acid by acidic methanolysis with typical yield of 15%. We also describe a method fo...

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Bibliografski detalji
Glavni autori: Li, Li, Shaik, Ahmad Ali, Zhang, Jinhui, Nhkata, Katai, Wang, Lei, Zhang, Yong, Xing, Chengguo, Kim, Sung-Hoon, Lü, Junxuan
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981694/
https://ncbi.nlm.nih.gov/pubmed/20970943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2010.09.028
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