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Anti-cancer gallotannin penta-O-galloyl-beta-D-glucose is a nanomolar inhibitor of select mammalian DNA polymerases

Penta-1,2,3,4,6-O-galloyl-beta-D-glucose (PGG) has been shown by us and others to inhibit the in vivo growth of human prostate cancer (PCa) xenografts in athymic nude mice and mouse lung cancer allograft in syngenic mice without evident adverse effect on their body weight. We observed a rapid inhibi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mizushina, Yoshiyuki, Zhang, Jinhui, Pugliese, Angelo, Kim, Sung-Hoon, Lü, Junxuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943143/
https://ncbi.nlm.nih.gov/pubmed/20599777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.031
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