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siRNA-Based Targeting of Cyclin E Overexpression Inhibits Breast Cancer Cell Growth and Suppresses Tumor Development in Breast Cancer Mouse Model

Cyclin E is aberrantly expressed in many types of cancer including breast cancer. High levels of the full length as well as the low molecular weight isoforms of cyclin E are associated with poor prognosis of breast cancer patients. Notably, cyclin E overexpression is also correlated with triple-nega...

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Bibliografiske detaljer
Main Authors: Liang, Yulong, Gao, Hong, Lin, Shiaw-Yih, Goss, John A., Brunicardi, Francis C., Li, Kaiyi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942895/
https://ncbi.nlm.nih.gov/pubmed/20877462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012860
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