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Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

The regulation of ACTH receptor binding sites and mRNA by ACTH and angiotensin II (A-II) was studied using cultured human adrenal fasciculata reticularis cells (HAC). These cells expressed two major ACTH receptor transcripts of 1.8 and 3.4 kb and three minor ones of 4, 7, and 11 kb. ACTH increased t...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Principais autores: Lebrethon, M C, Naville, D, Begeot, M, Saez, J M
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117168
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