Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

The regulation of ACTH receptor binding sites and mRNA by ACTH and angiotensin II (A-II) was studied using cultured human adrenal fasciculata reticularis cells (HAC). These cells expressed two major ACTH receptor transcripts of 1.8 and 3.4 kb and three minor ones of 4, 7, and 11 kb. ACTH increased t...

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Udgivet i:J Clin Invest
Main Authors: Lebrethon, M C, Naville, D, Begeot, M, Saez, J M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117168
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