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Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

The regulation of ACTH receptor binding sites and mRNA by ACTH and angiotensin II (A-II) was studied using cultured human adrenal fasciculata reticularis cells (HAC). These cells expressed two major ACTH receptor transcripts of 1.8 and 3.4 kb and three minor ones of 4, 7, and 11 kb. ACTH increased t...

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Pubblicato in:J Clin Invest
Autori principali: Lebrethon, M C, Naville, D, Begeot, M, Saez, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117168
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