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Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

The regulation of ACTH receptor binding sites and mRNA by ACTH and angiotensin II (A-II) was studied using cultured human adrenal fasciculata reticularis cells (HAC). These cells expressed two major ACTH receptor transcripts of 1.8 and 3.4 kb and three minor ones of 4, 7, and 11 kb. ACTH increased t...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Lebrethon, M C, Naville, D, Begeot, M, Saez, J M
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163681/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117168
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