Activation of H+ conductance in neutrophils requires assembly of components of the respiratory burst oxidase but not its redox function.

In phagocytes, superoxide generation by the NADPH oxidase is accompanied by metabolic acid production. Cytoplasmic acidification during this metabolic burst is prevented by a combination of H+ extrusion mechanisms, including a unique H+ conductance. NADPH oxidase is deficient in chronic granulomatou...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Nanda, A, Curnutte, J T, Grinstein, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8163676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117162
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!