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Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay.
A new immunoassay was developed to detect denaturation of type II collagen in osteoarthritis (OA). A peptide, alpha 1 (II)-CB11B, located in the CB11 peptide of type II collagen, was synthesized and used to produce a monoclonal antibody (COL2-3/4m) of the IgG1 (kappa) isotype. This reacts with a def...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1994
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294227/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117156 |
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