Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay.

A new immunoassay was developed to detect denaturation of type II collagen in osteoarthritis (OA). A peptide, alpha 1 (II)-CB11B, located in the CB11 peptide of type II collagen, was synthesized and used to produce a monoclonal antibody (COL2-3/4m) of the IgG1 (kappa) isotype. This reacts with a def...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Hollander, A P, Heathfield, T F, Webber, C, Iwata, Y, Bourne, R, Rorabeck, C, Poole, A R
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294227/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512992/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117156
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!