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Structure and Concentration Changes Affect Characterization of UGT Isoform-Specific Metabolism of Isoflavones

We characterized the isoform specific glucuronidation of six isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin using 12 expressed human UGTs and human intestinal and liver microsomes. The results indicated that these isoflavones are metabolized most rapidly at three...

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Detalhes bibliográficos
Main Authors: Tang, Lan, Singh, Rashim, Liu, Zhongqiu, Hu, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941769/
https://ncbi.nlm.nih.gov/pubmed/19545173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp8002557
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