The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters

OBJECTIVES: The biphasic kill curve of isoniazid against Mycobacterium tuberculosis in guinea pigs is due to the presence of persisters rather than selection of isoniazid-resistant mutants. To determine whether this phenomenon is common to other bactericidal drugs, we studied the activity of strepto...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ahmad, Zahoor, Pinn, Michael L., Nuermberger, Eric L., Peloquin, Charles A., Grosset, Jacques H., Karakousis, Petros C.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941674/
https://ncbi.nlm.nih.gov/pubmed/20693172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq277
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker