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Impact of the Mitochondrial Genetic Background in Complex III Deficiency

BACKGROUND: In recent years clinical evidence has emphasized the importance of the mtDNA genetic background that hosts a primary pathogenic mutation in the clinical expression of mitochondrial disorders, but little experimental confirmation has been provided. We have analyzed the pathogenic role of...

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Bibliografiska uppgifter
Huvudupphovsmän: Gil Borlado, Mari Carmen, Moreno Lastres, David, Gonzalez Hoyuela, Maritza, Moran, Maria, Blazquez, Alberto, Pello, Rosa, Marin Buera, Lorena, Gabaldon, Toni, Garcia Peñas, Juan Jose, Martín, Miguel A., Arenas, Joaquin, Ugalde, Cristina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941448/
https://ncbi.nlm.nih.gov/pubmed/20862300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012801
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