Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency

We have analyzed the cellular pathways and metabolic adaptations that take place in primary skin fibroblasts from patients with mutations in BCS1L, a major genetic cause of mitochondrial complex III enzyme deficiency. Mutant fibroblasts exhibited low oxygen consumption rates and intracellular ATP le...

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Detalhes bibliográficos
Publicado no:J Proteomics
Main Authors: Marín-Buera, Lorena, García-Bartolomé, Alberto, Morán, María, López-Bernardo, Elia, Cadenas, Susana, Hidalgo, Beatriz, Sánchez, Ricardo, Seneca, Sara, Arenas, Joaquín, Martín, Miguel A., Ugalde, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259860/
https://ncbi.nlm.nih.gov/pubmed/25239759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2014.09.007
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