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Respiratory chain enzyme deficiency induces mitochondrial location of actin-binding gelsolin to modulate the oligomerization of VDAC complexes and cell survival

Despite considerable knowledge on the genetic basis of mitochondrial disorders, their pathophysiological consequences remain poorly understood. We previously used two-dimensional difference gel electrophoresis analyses to define a protein profile characteristic for respiratory chain complex III-defi...

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Detalles Bibliográficos
Publicado en:Hum Mol Genet
Main Authors: García-Bartolomé, Alberto, Peñas, Ana, Marín-Buera, Lorena, Lobo-Jarne, Teresa, Pérez-Pérez, Rafael, Morán, María, Arenas, Joaquín, Martín, Miguel A., Ugalde, Cristina
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192415/
https://ncbi.nlm.nih.gov/pubmed/28431142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx144
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