Hypocretin and GABA Interact in the Pontine Reticular Formation to Increase Wakefulness

STUDY OBJECTIVES: Hypocretin-1/orexin A administered directly into the oral part of rat pontine reticular formation (PnO) causes an increase in wakefulness and extracellular γ-aminobutyric acid (GABA) levels. The receptors in the PnO that mediate these effects have not been identified. Therefore, th...

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Autors principals: Brevig, Holly N., Watson, Christopher J., Lydic, Ralph, Baghdoyan, Helen A.
Format: Artigo
Idioma:Inglês
Publicat: Associated Professional Sleep Societies, LLC 2010
Matèries:
Wakefulness and GABAA-Hypocretin Receptors
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941414/
https://ncbi.nlm.nih.gov/pubmed/21061850
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