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Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle

The molecular chaperone heat shock protein 90 (Hsp90) is an important and abundant protein in eukaryotic cells, essential for the activation of a large set of signal transduction and regulatory proteins. During the functional cycle, the Hsp90 dimer performs large conformational rearrangements. The t...

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Detalhes bibliográficos
Main Authors: Ratzke, C., Mickler, M., Hellenkamp, B., Buchner, J., Hugel, T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941327/
https://ncbi.nlm.nih.gov/pubmed/20736353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000916107
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