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Paracrinology of islets and the paracrinopathy of diabetes
New results have brought to light the importance of the regulation of glucagon by β-cells in the development of diabetes. In this perspective, we examine the normal paracrinology of α- and β-cells in nondiabetic pancreatic islets. We propose a Sherringtonian model of coordinated reciprocal secretory...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941311/ https://ncbi.nlm.nih.gov/pubmed/20798346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006639107 |
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