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Paracrinology of islets and the paracrinopathy of diabetes

New results have brought to light the importance of the regulation of glucagon by β-cells in the development of diabetes. In this perspective, we examine the normal paracrinology of α- and β-cells in nondiabetic pancreatic islets. We propose a Sherringtonian model of coordinated reciprocal secretory...

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Hlavní autoři: Unger, Roger H., Orci, Lelio
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941311/
https://ncbi.nlm.nih.gov/pubmed/20798346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006639107
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