Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions

Active Src localization at focal adhesions (FAs) is essential for cell migration. How this pool is linked mechanistically to the large pool of Src at late endosomes (LEs)/lysosomes (LY) is not well understood. Here, we used inducible Tsg101 gene deletion, TSG101 knockdown, and dominant-negative VPS4...

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Detalhes bibliográficos
Main Authors: Tu, Chun, Ortega-Cava, Cesar F., Winograd, Paul, Stanton, Marissa Jo, Reddi, Alagarsamy Lakku, Dodge, Ingrid, Arya, Ranjana, Dimri, Manjari, Clubb, Robert J., Naramura, Mayumi, Wagner, Kay-Uwe, Band, Vimla, Band, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941294/
https://ncbi.nlm.nih.gov/pubmed/20805499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009471107
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