Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions

Active Src localization at focal adhesions (FAs) is essential for cell migration. How this pool is linked mechanistically to the large pool of Src at late endosomes (LEs)/lysosomes (LY) is not well understood. Here, we used inducible Tsg101 gene deletion, TSG101 knockdown, and dominant-negative VPS4...

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Bibliographische Detailangaben
Hauptverfasser: Tu, Chun, Ortega-Cava, Cesar F., Winograd, Paul, Stanton, Marissa Jo, Reddi, Alagarsamy Lakku, Dodge, Ingrid, Arya, Ranjana, Dimri, Manjari, Clubb, Robert J., Naramura, Mayumi, Wagner, Kay-Uwe, Band, Vimla, Band, Hamid
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941294/
https://ncbi.nlm.nih.gov/pubmed/20805499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009471107
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