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Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

Posttranslational modification of amino acids confers a range of structural features and activities on ribosomally synthesized peptides, many of which have potent antimicrobial or other biological activities. Cypemycin is an extensively modified linear peptide produced by Streptomyces sp. OH-4156 wi...

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Detalles Bibliográficos
Main Authors: Claesen, Jan, Bibb, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941285/
https://ncbi.nlm.nih.gov/pubmed/20805503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008608107
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