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Genome mining and genetic analysis of cypemycin biosynthesis reveal an unusual class of posttranslationally modified peptides

Posttranslational modification of amino acids confers a range of structural features and activities on ribosomally synthesized peptides, many of which have potent antimicrobial or other biological activities. Cypemycin is an extensively modified linear peptide produced by Streptomyces sp. OH-4156 wi...

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Bibliografiske detaljer
Main Authors: Claesen, Jan, Bibb, Mervyn
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941285/
https://ncbi.nlm.nih.gov/pubmed/20805503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008608107
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