The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

MicroRNAs (miRNAs) are important regulators of cell fate determination and homeostasis. Expression of these small RNA genes is tightly regulated during development and in normal tissues, but they are often misregulated in cancer. MiRNA expression is also affected by DNA damaging agents, such as radi...

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Bibliografiske detaljer
Main Authors: Kato, M, Paranjape, T, Ullrich, R, Nallur, S, Gillespie, E, Keane, K, Esquela-Kerscher, A, Weidhaas, JB, Slack, FJ
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941141/
https://ncbi.nlm.nih.gov/pubmed/19421141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.106
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