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Reciprocal Expression of lin-41 and the microRNAs let-7 and mir-125 During Mouse Embryogenesis

In C. elegans, heterochronic genes control the timing of cell fate determination during development. Two heterochronic genes, let-7 and lin-4, encode microRNAs (miRNAs) that down-regulate a third heterochronic gene lin-41 by binding to complementary sites in its 3’UTR. let-7 and lin-4 are conserved...

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Detalhes bibliográficos
Main Authors: Schulman, Betsy R. Maller, Esquela-Kerscher, Aurora, Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596717/
https://ncbi.nlm.nih.gov/pubmed/16247770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20599
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