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The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure

In the nematode Caenorhabditis elegans, the let-7 microRNA (miRNA) controls the timing of key developmental events and terminal differentiation in part by directly regulating lin-41. C. elegans lin-41 mutants display precocious cell cycle exit and terminal differentiation of epidermal skin cells. li...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schulman, Betsy R. Maller, Liang, Xianping, Stahlhut, Carlos, DelConte, Casey, Stefani, Giovanni, Slack, Frank J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895810/
https://ncbi.nlm.nih.gov/pubmed/19098426
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