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The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

MicroRNAs (miRNAs) are important regulators of cell fate determination and homeostasis. Expression of these small RNA genes is tightly regulated during development and in normal tissues, but they are often misregulated in cancer. MiRNA expression is also affected by DNA damaging agents, such as radi...

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Detalhes bibliográficos
Main Authors: Kato, M, Paranjape, T, Ullrich, R, Nallur, S, Gillespie, E, Keane, K, Esquela-Kerscher, A, Weidhaas, JB, Slack, FJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941141/
https://ncbi.nlm.nih.gov/pubmed/19421141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.106
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