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ProbKnot: Fast prediction of RNA secondary structure including pseudoknots

It is a significant challenge to predict RNA secondary structures including pseudoknots. Here, a new algorithm capable of predicting pseudoknots of any topology, ProbKnot, is reported. ProbKnot assembles maximum expected accuracy structures from computed base-pairing probabilities in O(N(2)) time, w...

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Bibliographic Details
Main Authors: Bellaousov, Stanislav, Mathews, David H.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941096/
https://ncbi.nlm.nih.gov/pubmed/20699301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2125310
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