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Deficiency of Splicing Factor 1 suppresses occurrence of testicular germ cell tumors

Testicular germ cell tumors (TGCTs) originate from germ cells. The 129-Ter and M19 (129.MOLF-Chr19 consomic) mouse strains have extremely high incidences of TGCTs. We found that the expression levels of Sf1 encoded Splicing factor 1 (SF1) can modulate the incidence of TGCTs. We generated mice with i...

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Main Authors: Zhu, Rui, Heaney, Jason, Nadeau, Joseph H., Ali, Sara, Matin, Angabin
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940986/
https://ncbi.nlm.nih.gov/pubmed/20736371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0820
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