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Deficiency of Splicing Factor 1 suppresses occurrence of testicular germ cell tumors
Testicular germ cell tumors (TGCTs) originate from germ cells. The 129-Ter and M19 (129.MOLF-Chr19 consomic) mouse strains have extremely high incidences of TGCTs. We found that the expression levels of Sf1 encoded Splicing factor 1 (SF1) can modulate the incidence of TGCTs. We generated mice with i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940986/ https://ncbi.nlm.nih.gov/pubmed/20736371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0820 |
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