Role of transporter-mediated efflux in the placental biodisposition of bupropion and its metabolite, OH-bupropion

Cigarette smoking during pregnancy is a preventable risk factor associated with maternal and fetal complications. Bupropion is an antidepressant used successfully for smoking cessation in non-pregnant patients. Our goal is to determine whether it could benefit the pregnant patient seeking smoking ce...

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Bibliographic Details
Main Authors: Hemauer, Sarah J., Patrikeeva, Svetlana L., Wang, Xiaoming, Abdelrahman, Doaa R., Hankins, Gary D.V., Ahmed, Mahmoud S., Nanovskaya, Tatiana N.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940852/
https://ncbi.nlm.nih.gov/pubmed/20599802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.025
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