Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers

BACKGROUND: Genomic gains and losses are a result of genomic instability in many types of cancers. BRCA1- and BRCA2-mutated breast cancers are associated with increased amounts of chromosomal aberrations, presumably due their functions in genome repair. Some of these genomic aberrations may harbor g...

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Autores principales: Holstege, Henne, van Beers, Erik, Velds, Arno, Liu, Xiaoling, Joosse, Simon A, Klarenbeek, Sjoerd, Schut, Eva, Kerkhoven, Ron, Klijn, Christiaan N, Wessels, Lodewyk FA, Nederlof, Petra M, Jonkers, Jos
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940799/
https://ncbi.nlm.nih.gov/pubmed/20735817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-455
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