Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.

We have shown previously that interleukin 1 (IL-1) stimulates eicosanoid production in glomerular mesangial cells (MC) by de novo synthesis of a 14-kD, group II phospholipase A2 (PLA2). IL-1-stimulated prostaglandin E2 synthesis precedes expression of this enzyme, suggesting that another PLA2 isofor...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Gronich, J, Konieczkowski, M, Gelb, M H, Nemenoff, R A, Sedor, J R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8132762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117076
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