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Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells.

Potent pro-inflammatory cytokines, such as interleukin 1 (IL-1) or tumor necrosis factor (TNF) alpha have been found to increase group II phospholipase A2 (PLA2) synthesis and secretion by mesangial cells. In all cases 85-90% of the enzyme is secreted from the cells and a parallel increase in prosta...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pfeilschifter, J, Schalkwijk, C, Briner, V A, van den Bosch, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8227364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116860
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