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Effect of Correlated tRNA Abundances on Translation Errors and Evolution of Codon Usage Bias

Despite the fact that tRNA abundances are thought to play a major role in determining translation error rates, their distribution across the genetic code and the resulting implications have received little attention. In general, studies of codon usage bias (CUB) assume that codons with higher tRNA a...

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Bibliografiske detaljer
Main Authors: Shah, Premal, Gilchrist, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940732/
https://ncbi.nlm.nih.gov/pubmed/20862306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001128
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