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Explaining complex codon usage patterns with selection for translational efficiency, mutation bias, and genetic drift

The genetic code is redundant with most amino acids using multiple codons. In many organisms, codon usage is biased toward particular codons. Understanding the adaptive and nonadaptive forces driving the evolution of codon usage bias (CUB) has been an area of intense focus and debate in the fields o...

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Autori principali: Shah, Premal, Gilchrist, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121864/
https://ncbi.nlm.nih.gov/pubmed/21646514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016719108
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