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Effect of Correlated tRNA Abundances on Translation Errors and Evolution of Codon Usage Bias

Despite the fact that tRNA abundances are thought to play a major role in determining translation error rates, their distribution across the genetic code and the resulting implications have received little attention. In general, studies of codon usage bias (CUB) assume that codons with higher tRNA a...

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Détails bibliographiques
Auteurs principaux: Shah, Premal, Gilchrist, Michael A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940732/
https://ncbi.nlm.nih.gov/pubmed/20862306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001128
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