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Correlated Mutations: A Hallmark of Phenotypic Amino Acid Substitutions

Point mutations resulting in the substitution of a single amino acid can cause severe functional consequences, but can also be completely harmless. Understanding what determines the phenotypical impact is important both for planning targeted mutation experiments in the laboratory and for analyzing n...

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書誌詳細
主要な著者: Kowarsch, Andreas, Fuchs, Angelika, Frishman, Dmitrij, Pagel, Philipp
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940720/
https://ncbi.nlm.nih.gov/pubmed/20862353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000923
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