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Correlated Mutations: A Hallmark of Phenotypic Amino Acid Substitutions

Point mutations resulting in the substitution of a single amino acid can cause severe functional consequences, but can also be completely harmless. Understanding what determines the phenotypical impact is important both for planning targeted mutation experiments in the laboratory and for analyzing n...

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Bibliografische gegevens
Hoofdauteurs: Kowarsch, Andreas, Fuchs, Angelika, Frishman, Dmitrij, Pagel, Philipp
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940720/
https://ncbi.nlm.nih.gov/pubmed/20862353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000923
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